The Global Stress & Resilience Network proudly announces the 2024 Pioneer Award to Ron de Kloet and Marian Joëls, in recognition of their groundbreaking collaborative and individual contributions to the field of stress and brain research. Their work has significantly deepened our understanding of how stress affects the brain and behavior, particularly the roles of glucocorticoids and neuroplasticity in shaping resilience.

Ron de Kloet‘s seminal work has been pivotal in understanding glucocorticoid hormones’ complex roles in stress responses. His significant discovery of the Mineralocorticoid Receptor (MR) and its balance with the Glucocorticoid Receptor (GR) has revealed the critical role of cortisol in shifting brain function from protective to harmful states in stress-related disorders. His extensive research has significantly contributed to the understanding of stress mechanisms and their implications for mental health.

Marian Joëls‘ impactful contributions have been instrumental in elucidating the effects of stress hormones on the brain, especially in synaptic function and structure in the hippocampus. Her research on the time-dependent effects of stress hormones has brought new insights into how stress impacts brain function and behavior over varying durations. Joëls’ extensive study of stress hormones’ broader implications on neural circuits has significantly advanced the fields of neuroendocrinology and psychiatric disorders.

The Global Stress & Resilience Network Pioneer Award celebrates these exceptional scientists, whose shared and individual legacies continue to inspire and drive forward the field of stress science, opening new avenues for understanding and managing stress-related conditions.

The award ceremony will take place during the Stress & Resilience conference on April 15, 2024 and will be followed by an aperitif in honor of the winners.